Three-Dimensional Molecular Modeling of Bovine Caseins: αs1-Casein
نویسندگان
چکیده
منابع مشابه
Exploring the Interaction Mechanism of Coumarin with Bovine β-Casein: Spectrofluorometric and Molecular Modeling Studies
This paper is designed to examine the binding behavior of Coumarin with bovine -casein (βCN) through fluorescence spectroscopy and molecular modeling techniques. The data analysis on fluorescence titration experiments at various temperatures represents the enthalpy driven nature for the formation of Coumarin–βCN complex and the prevailed role of hydrogen bonds and van der Waals interactions in...
متن کاملMutational analysis of major IgE-binding epitopes of recombinant bovine αS1-casein
Background Cow’s milk allergy (CMA) is one of the most widespread human allergies, especially in very young children. One of the main bovine milk allergen is aS1-casein which is considered as intrinsically unfolded protein. Its epitope determinants have been partially characterized using synthetic peptides and crucial amino acid residues for IgE-binding have been identified. However, this very ...
متن کاملStudies on casein. 2. The action of phosphatases on caseins and low-molecular-weight phosphates.
1. An improved method for the preparation of phosphoprotein phosphatase from ox spleen is described. The enzyme was purified 60-fold with a yield of 21 %. 2. The enzyme preparation was free from proteolytic activity and had no action on fl-glycerol phosphate. 3. The enzyme was active on caseins, phenyl phosphate and inorganic pyrophosphate. Hence it cannot be described as a specific phosphoprot...
متن کاملA preparation of cow's late colostrum fraction containing αs1-casein promoted the proliferation of cultured rat intestinal IEC-6 epithelial cells.
Colostrum is a complex mixture of bioactives that promotes neonate growth. Recently, we have found by in vivo study that skimmed, sterilized, and concentrated bovine late colostrum (SCBLC), obtained from a Holstein herd on days 6-7 after parturition, had an ability to maintain intestinal integrity. In the present study we investigated effects of SCBLC on rat intestinal IEC-6 cell proliferation ...
متن کاملAutoantibodies to αS1-Casein Are Induced by Breast-Feeding
BACKGROUND The generation of antibodies is impaired in newborns due to an immature immune system and reduced exposure to pathogens due to maternally derived antibodies and placental functions. During nursing, the immune system of newborns is challenged with multiple milk-derived proteins. Amongst them, caseins are the main constituent. In particular, human αS1-casein (CSN1S1) was recently shown...
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 1991
ISSN: 0022-0302
DOI: 10.3168/jds.s0022-0302(91)78470-1